Amir Khan will face Andreas Kotelnik of Ukraine for the WBA world light-welterweight title in 27th June.
Khan defeated Mexican legend Marco Antonio Barrera in their lightweight contest in Manchester last month.
Kotelnik has never been stopped, is no stranger to Britain, having fought three times there already.
"To fight for the world title in only my 22nd fight is fantastic," said Khan.
"This is the best news that I could have received. Frank has done a great job getting the world title fight for me in Britain and now I have to go out and win it.
"I've seen Kotelnik a few times and I've always been impressed by him but once my trainer Freddie Roach works out the game plan to beat him it's my job to execute it on the night, as I did effectively against Barrera."
Promoter Frank Warren said: "This is the moment that Amir has been waiting for and I'm delighted to deliver him the opportunity.
"Amir put in a sensational performance against a three-time world champion and future Hall of Famer in Barrera in only his 21st fight and now he has to produce the same form against Kotelnik, who is a good hard fighter."
